PTT detects nearly all abnormalities in clotting, due to deficiencies in
clotting factors or circulating anticoagulants.
It is frequently used to monitor heparin therapy.
A modification of the test, "Activated PTT," or APTT, is
basically the same as PTT, but is slightly more sensitive.
Prolonged PTT is associated with:
- Liver disease
- Vitamin K deficiency
- Anticoagulant (Coumarin, Coumadin, Heparin) therapy
Therapeutic Range (Heparin Therapy)
Therapeutic Range on oral anticoagulants
||2-2.5 times normal
*These are general values taken from a variety of
sources. The actual normal values may vary from lab to lab and from one
type of testing protocol to another.