Norethindrone and Ethinyl Estradiol (Lo Estrin 1.5/30)

Category:

  • Hormonal

Description:

  • Monophasic oral contraceptive

  • Lo Estrin: norethindrone 1.5mg, ethinyl estradiol 30mcg

Indications:

  • Contraceptive

Contraindications:

  • Pregnancy and lactation

  • Undiagnosed abnormal vaginal bleeding

  • Known or suspected benign or malignant liver tumors while on oral contraceptive use

  • Breast carcinoma or estrogen-dependent neoplasia
  • Current or history of thromboembolic disorders, cerebral vascular or cardiovascular disease.

Precautions:

  • Pregnancy category X

  • Take as directed at intervals not exceeding 24 hours.  Efficiency is dependent upon strict compliance.

  • Breakthrough bleeding (“spotting”) may occur during initiation of therapy.

  • Instructions for missed doses:

    • One missed dose: Take as soon as possible or two tablets the next day and continue

    • Two missed doses: Take two tablets daily for two days, then continue normal schedule

    • Three missed doses: Discontinue therapy and begin new packet 7 days following last dose

  • May cause mental depression, fluid retention and depressed folate levels

  • Twenty-eight day packs contain seven days of inert ingredients to maintain regimen

  • Begin therapy on the fifth day of the cycle.  Day one of cycle is the first day of menstrual bleeding.

Adverse Reactions (Side Effects):

  • Abdominal cramping, anorexia, nausea, vomiting

  • Acne

  • Edema, weight gain

  • Unusual tiredness or weakness

  • Cardiovascular disorders (hypertension)

  • Thromboembolic disorders

Dosage:

Administered orally

  • One tablet daily for 21 or 28 days beginning on the fifth day of the cycle

Source: Operational Medicine 2001,  Health Care in Military Settings, NAVMED P-5139, May 1, 2001, Bureau of Medicine and Surgery, Department of the Navy, 2300 E Street NW, Washington, D.C., 20372-5300  

Gynecology and Obstetrics CD-ROM
Volumes 1-6
2004 Edition
Lippincott Williams & Wilkins
Copyright 2004
All Rights Reserved