Fig. 1. Intracytoplasmic sperm injection (ICSI). A. A sperm is immobilized after the sperm tail is touched by the injection pipette. B. The injection pipette carrying a sperm is piercing the zona pellucida. C. The injection pipette applies suction on the oolemma to break it. D. The oolemma is broken and the sperm is delivered inside the ooplasm.