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Name: Michael P. Diamond, MD

Affiliation: Associate Chair and Kamran S. Moghissi Professor of Obstetrics and Gynecology Director, Division of Reproductive Endocrinology and Infertility Assistant Dean for Clinical and Translational Research Wayne State University School of Medicine

Chapters Contributed: Surgical Aspects of Infertility

General Biographical Description: Michael P. Diamond, MD, is the Kamran S. Moghissi Professor and associate chair of the Department of Obstetrics and Gynecology at Wayne State University School of Medicine. After completing undergraduate studies at Vassar College in Poughkeepsie, New York, he completed medical school at Vanderbilt University in Nashville, Tennessee, followed by internship and residency in obstetrics and gynecology at the same institution; he subsequently completed a fellowship in reproductive endocrinology and infertility at Yale University in New Haven, Connecticut. Dr. Diamond was American Board of Obstetrics and Gynecology (ABOG) certified in obstetrics and gynecology in 1989 and in reproductive endocrinology and infertility in 1991; he was recertified in each in 1997. He received a Clinical Associate Physician (CAP) award from the Yale University General Clinical Research Center. He was on the faculty at Yale University for more than 5 years before returning to Vanderbilt University as director of the Division of Reproductive Endocrinology and Infertility. In 1994, Dr. Diamond moved to Wayne State University (WSU) to become director of the Division of Reproductive Endocrinology and Infertility and professor in the Department of Obstetrics and Gynecology. Dr. Diamond has been the director of the WSU REI fellowship program since shortly after his arrival at WSU in 1995. He has served on general clinical research advisory (GCRC) boards at three institutions, Yale University, Vanderbilt University, and University of Michigan (while at WSU). He has specific expertise, interest, and experience in the development of postoperative adhesions, carbohydrate metabolism, androgen physiology, and the induction of ovulation. Dr. Diamond has extensive experience in research study design, organization, and implementation. He has a long track record of conduct of prospective clinical studies, as well as randomized controlled clinical trials. As a resident at Vanderbilt University, he organized a multicenter study examining the value of lasers for conduct of surgical procedures and its effects on postoperative adhesion development after laparotomy. These seminal studies led to the classification (and differentiation) of de novo adhesions from adhesion re-formation. Subsequently, he conducted a similar trial examining adhesion development after laparoscopic surgery. He has played leading roles in design and conduct of the preclinical/clinical studies leading to FDA approval of the first two agents for reduction of postoperative intra-abdominal adhesions approved and available in the United States (Interceed and Seprafilm). Dr. Diamond has been funded by the NICHD to conduct randomized clinical trials using euglycemic hyperinsulinemic and hypoglycemic clamp techniques to evaluate the role of androgens on insulin principal investigator (PI) on the NICHD Cooperative Reproductive Medicine Network grant, which has conducted clinical trials on diagnosis of luteal phase defects and ovulation induction for women with polycystic ovarian syndrome. He has participated in the NICHD National Cooperative Program for Infertility Research (U54 HD 34449) examining hormonal perturbations in women with otherwise 'unexplained' infertility and has collaborated in trials examining the effect of organochlorines on male factor infertility funded by NIEHS; studies examining the effect of testosterone replacement on cognitive function in hypogonadal men funded by NIH-NIA; and studies on the effect of sex steroids and gender on apneic thresholds funded by the VA. Dr. Diamond has also served as PI or co-PI on more than 25 commercial clinical trials. He has served on multiple study sections and special review committees for the NIH, the State of Indiana, and for granting agencies in the United Kingdom and Belgium. Dr. Diamond has also served for 4 years on the Obstetrics and Gynecology Device Panel of the Center for Devices and Radiological Health of the Food and Drug Administration and is now serving his third 4-year term as a consultant to that agency. In this capacity, Dr. Diamond has helped design FDA guidance documents that have become the basis for clinical trials submitted to the agency on these topics. He currently is vice chair of the WSU M01 IRB, and has served as a member of the WSU IRB Steering Committee. He is actively involved in enhancing infrastructure and educational opportunities to provide clinical and translational research.

Special Interests: Postoperative Adhesion Development, Infertility Surgery, Clinical and Translational Research, Clinical Trials, Carbohydrate Metabolism

Contact Address: 3750 Woodward Avenue, Suite 200-D, Detroit, Michigan 48201, USA Phone: (313) 993-4523