Cryoglobins are unusual proteins that precipitate out of solution at low temperatures and reversibly re-dissolve on warming. Their presence is associated with:
Auto-immune diseases, including:
Poststreptococcal glomerulonephritis
Rheumatoid arthritis
Lupus
Sjoegren's syndrome
Polyarteritis nodosum
Infectious illnesses, including:
Mononucleosis
Syphilis
Cytomegalovirus
Leprosy
Sarcoidosis
Malignancies, specifically:
Multiple myeloma
Chronic lymphocytic leukemia
Lymphosarcoma
Liver disease, hemolytic disease, and ulcerative colitis
Normal Values*
Men-Women
Negative
*These are general values taken from a variety of sources. The actual normal values may vary from lab to lab and from one type of testing protocol to another.
