DHEAS is produced primarily in the adrenal gland, where it reflects adrenal androgen production.
Normal levels of DHEAS make adrenal disease very unlikely.
Moderate increases in DHEAS are associated with:
Anovulation/amenorrhea
Polycystic ovary syndrome
Hyperprolactinemia
Marked elevations of DHEAS are associated with large increases in circulating testosterone, produced either directly by the adrenal gland, gonads, or by peripheral conversion.
Normal Values*
Men
80-640 µg/dl
217-1740 µmol/L
Women
< 350 µg/dl
< 950 µmol/L
Women: Moderate Increase
350-700 µg/dl
950-1900 µmol/L
Women: High Levels
> 700 µg/dl
> 1900 µmol/L
*These are general values taken from a variety of sources. The actual normal values may vary from lab to lab and from one type of testing protocol to another.
