Severe infection during pregnancy, at birth or
after birth
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Written by experienced doctors, midwives and other medical professionals – and approved by a specialist Editorial Board
Enhancing the Welfare of Women
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The Welfare of Women program has been created under the General Editorship of Dr Kate Lightly, University of Liverpool, UK and is overseen by an expert International Editorial Board
The cost of producing this resource has been partly funded by an educational grant from GSK
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Infections are common during pregnancy, birth and after birth. Sometimes, these infections can enter the blood, spread quickly through the body and damage major organs. When this happens, it is called maternal sepsis. If it is not treated quickly, maternal sepsis can be very dangerous and even life-threatening.
Maternal sepsis is one of the main causes of death in women during pregnancy, childbirth and after birth. It can also affect your baby, causing an early birth or sometimes infections in the baby or death.
It can be lifesaving to learn about sepsis so that you know when to go to a healthcare facility if you think that you have sepsis. With the proper care, sepsis can be treated and your life and your baby's can be saved.
Infections are the most common cause of maternal sepsis. These infections can happen:
You may also be more at risk of maternal sepsis if you
You might have maternal sepsis if you
Especially if you
If you notice any of these symptoms, you need to go to your nearest healthcare facility straight away. Do not wait. Sepsis can get worse quickly and can even end your life.
If you think you have maternal sepsis, your healthcare worker will check you and your baby and
To treat maternal sepsis, your healthcare worker may give you
Treatment for sepsis should start as soon as possible, preferably within an hour of it being recognized. You may need to stay in the hospital to be monitored, and the baby may be born early.
You can lower your chances of maternal sepsis by
These steps can help protect you and your baby from dangerous infections that cause sepsis.
The authors of this MATERNAL SEPSIS program are:
The Welfare of Women program has been created under the General Editorship of Dr Kate Lightly, University of Liverpool, UK and is overseen by an expert International Editorial Board
The publishing reference for this program is: DOI 10.3843/GLOWM.w10093
The Welfare of Women information program is an attempt to provide women everywhere with access to reliable information about key health issues that may be relevant to them. Information is offered at three separate levels which women may select according to their preferences; firstly, short video animations with voice commentary, secondly, more detailed text-based descriptions, and thirdly, links to recommended further reading. With the animated videos, women can also select the images that they feel most comfortable in viewing from a short range of very generalized and non-specific ethnicity options. Because of the special programming used, both the videos and the text information can – when authorized – be translated into any language in a simple and rapid manner.
The following websites provide more comprehensive and extensive information on this topic, which is both reliable and strongly recommended for readers who want to learn more than the details provided above:
World Health Organization (WHO), Maternal Sepsis Page
https://www.who.int/teams/sexual-and-reproductive-health-and-research-(srh)/areas-of-work/maternal-and-perinatal-health/maternal-sepsis
WHO, How to Prevent Sepsis
https://www.who.int/multi-media/details/how-to-prevent-sepsis
WHO, Global Maternal and Neonatal Sepsis Initiative (GLOSS)
https://pubmed.ncbi.nlm.nih.gov/32353314/
Global Maternal and Neonatal Sepsis Initiative
https://srhr.org/sepsis/
International Federation of Gynaecology and Obstetrics (FIGO), Preventing Sepsis After Birth
https://www.figo.org/news/new-ijgo-review-provides-comprehensive-framework-preventing-post-caesarean-sepsis
The UK Sepsis Trust, Maternal Sepsis
https://sepsistrust.org/about-sepsis/maternal-sepsis/
Royal College of Obstetricians and Gynaecologists (RCOG) – Identification and management of maternal
sepsis during and following pregnancy (Green-top Guideline No. 64)
https://www.rcog.org.uk/guidance/browse-all-guidance/green-top-guidelines/identification-and-management-of-maternal-sepsis-during-and-following-pregnancy-green-top-guideline-no-64/
WHO, GLOSS Study
https://pubmed.ncbi.nlm.nih.gov/32353314/
WHO, Recommendations for Prevention and Treatment of Maternal Peripartum Infections
https://www.who.int/publications/i/item/9789241549363
WHO, Water, Sanitation, and Hygiene in Health Care Facilities
https://www.who.int/publications/i/item/9789241515511
WHO, Standards for Improving Quality of Maternal and Newborn Care in Health Facilities
https://www.who.int/publications/i/item/9789241511216
WHO, Guidelines on Hand Hygiene in Health Care
https://www.who.int/publications/i/item/9789241597906
The Surviving Sepsis Campaign Bundle (2018)
https://pubmed.ncbi.nlm.nih.gov/29675566/